Abstract
Averrhoa bilimbi is one of the India’s most legendary and sacred trees which belongs to the family Oxalidaceae.The aim of the current study is to examine the hepatoprotective effect of ethanolic leaf extracts of Averrhoa bilimbi against alcohol-induced hepatic damage in albino rats.The degree of protection was determined by evaluating biochemical parameters such as serum Alanine transaminase, Aspartate transaminase,Serum alkaline phosphatase, and total Bilirubin.The study reveals,when compared to the positive control, the leaf extract at dose levels of 100, 200, and 400mg/kg bodyweight p.o. showed a significant (P<0.05) reduction in liver enzyme levels. The histopathological examination of liver sections were supported by these biochemical parameters. The phytochemical analysis of the extract shows the presence of phytosterols and flavonoids, which might be responsible for the hepatoprotective activity.Therefore it could be concluded that Averrhoa bilimbi leaves extract possess potent hepatoprotective activity against alcohol induced hepatic damage in rats.
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