Abstract

AbstractBiliary tract cancers exhibit various modes of local extension, and some can only be resected by hepatopancreatoduodenectomy (HPD), which is defined as the resection of the whole extrahepatic biliary system with the adjacent liver and pancreatoduodenum. Early experiences with HPD were frequently associated with liver failure and subsequent mortality. However, with improvements in surgical techniques and perioperative patient care, the mortality rate after HPD has gradually reduced. Recent studies on HPD, although limited, have demonstrated a favorable survival in cholangiocarcinoma; whereas, controversial benefit in gallbladder cancer because of the extremely poor survival. HPD is a standard approach for laterally-spreading cholangiocarcinoma that is otherwise unresectable.KeywordsHepatopancreatoduodenectomyCholangiocarcinoma

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