Abstract
Introduction: Liver cirrhosis is common in Bangladesh. There has been a rise in acute viral E hepatitis in Bangladesh after the 2004 flood. At that time most of the country was under water for more than a month leading to sewerage contamination of water supply. The aim of this study was to assess the role of HEV infection in causing decompensation of cirrhosis. Materials and Methods: In this retrospective study, 69 patients with evidence of cirrhosis were included. They presented between January 2005 to January 2006 with features of decompensation for the first time. Anti-HEV IgM and anti-HAV IgM were tested and history of upper GI haemorrhage, drug and alcohol intake recorded. Results: Anti-HEV IgM was positive in 21.7% (15/69) patients. 4.3% (3/69) had history of upper GI haemorrhage and 4.3% (3/69) history of alcohol intake or diuretic overdose or anti-tuberculotic drugs. None tested positive for anti-HAV IgM. No cause for decompensation was found in others. It is likely that decompensation in these pa...
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