Abstract

Hepatitis E Nanoparticle: A Capsid-Based Platform for Non-Invasive Vaccine Delivery and Imaging-Guided Cancer Treatment

Highlights

  • Today’s medicine revolves around a “standards of care” to employ the best approach towards treatment and prevention for the general public

  • Major efforts are invested towards the development of therapeutic delivery via non-invasive routes to increase patient compliance and enhance targeting accuracy

  • A potent and effective delivery system must be equipped with following characteristics: It must be safe, biocompatible, and biodegradable; have high encapsulation efficiency and surface modification properties to enhance targeting accuracy, while

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Summary

Introduction

Today’s medicine revolves around a “standards of care” to employ the best approach towards treatment and prevention for the general public. A growing trend is aimed towards exploring precision medicine to meet the needs for each individual, . Non-specific delivery of drugs leads to suboptimal results and high toxicity [2]. Major efforts are invested towards the development of therapeutic delivery via non-invasive routes to increase patient compliance and enhance targeting accuracy. In nanodelivery systems has elevated the significance of personalized and precision medicine. Despite tremendous effort in design and development of effective drug delivery systems, overcoming biological barriers and achieving successful accumulation of nanotherapeutics at targeted site remains a challenge [3]. The primary focus in both pharmaceutical sciences and nanotechnology is to 1) enhance drug targeting and delivery, 2) reduce toxicity, 3) and achieve greater safety and biocompatibility [4]

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