Abstract

The seroprevalence to hepatitis E virus (HEV; IgG and total antibodies) in Nigeria lies between 7.0‑66.75% in different populations. This is due to the fact that only a limited number of studies have been performed on the seroprevalence of (HEV). In the present study, demographics, the associated risk and the behavioral characteristics of blood donors were identified based on direct and indirect questions. These were applied to those who gave their consent to participate in the study. Purposive sampling was employed following the principle of gradual selection and multinomial regression analysis was applied. The seroprevalence of HEV in different centers investigated in the present study indicated the high prevalence of HEV infection among blood donors in Southwest Nigeria. The findings of the present study therefore reveal the risks associated with the presence of HEV in blood donor samples, and the potential for this infection to be transmitted to others via blood transfusion.

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