Hepatitis C virus non-structural 3/4A protein interferes with intrahepatic interferon-γ production

Erwin Daniel Brenndörfer,Johannes Georg Bode,Jonas Söderholm,Soo Aleman,Anette Brass,Matti Sällberg,Lars Frelin

doi:10.1136/gut.2010.232116

Hepatitis C virus non-structural 3/4A protein interferes with intrahepatic interferon-γ production

Erwin Daniel Brenndörfer, Johannes Georg Bode + Show 5 more

https://doi.org/10.1136/gut.2010.232116

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Journal: Gut	Publication Date: Aug 3, 2011
Citations: 15

Affiliation: Karolinska University Hospital, Karolinska Institutet, Heinrich Heine University Düsseldorf, Düsseldorf University Hospital, University of Gothenburg, Inovio Pharmaceuticals (United States)

#TIR Domain-containing Adaptor Inducing IFNβ #T-cell Protein Tyrosine Phosphatase + Show 8 more

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BackgroundThe non-structural (NS) 3/4A protease/helicase of the hepatitis C virus is known to modulate signalling pathways in the infected hepatocyte by cleaving CARD adaptor inducing IFNβ (Cardif), T-cell protein tyrosine...

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