Abstract

Hepatitis A and hepatitis E are the leading causes of acute viral hepatitis in developing countries due to our poor sanitaryconditions, both spread by fecal-oral route or through contaminated water and food. Being both self-limiting diseases, they are usually benign but may present with atypical clinical findings. A 32 year-old female with right pleural effusion, ascites and acalculous cholecystitis during the course of HAV and HEV co-infection is reported. Clinical improvement was observed with conservative management. As far as we know, this is the first case described of a patient with these three complications in thebackground of a hepatitis A virus and hepatitis E virus co-infection.

Highlights

  • Both hepatitis A virus (HAV) and hepatitis E virus (HEV) are leading causes of acute viral hepatitis in developing countries due to poor sanitary conditions

  • Hepatitis A is generally an acute, self-limiting liver infection transmitted through the fecal-oral route by a positive-strand RNA virus, the hepatitis A virus (HAV), which causes 10 million infections worldwide each year . [10] Serological and molecular studies have shown that hepatitis E virus (HEV) is globally distributed and is the leading cause of enterically transmitted viral hepatitis illness worldwide

  • It is estimated that two billion people worldwide are infected with HEV every year, with 14 million symptomatic cases and 300,000 deaths . [11] Considering the similar epidemiological profile of both viruses, it is unsurprising that a dual infection is not uncommon

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Summary

REPORTE DE CASO

Hepatitis A and hepatitis E virus co-infection with right pleural effusion, ascites and acute acalculous cholecystitis. Coinfección por el virus de la hepatitis A y la hepatitis E con derrame pleural derecho, ascitis y colecistitis acalculosa aguda.

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