Abstract
Hepatitis A and hepatitis E are the leading causes of acute viral hepatitis in developing countries due to our poor sanitaryconditions, both spread by fecal-oral route or through contaminated water and food. Being both self-limiting diseases, they are usually benign but may present with atypical clinical findings. A 32 year-old female with right pleural effusion, ascites and acalculous cholecystitis during the course of HAV and HEV co-infection is reported. Clinical improvement was observed with conservative management. As far as we know, this is the first case described of a patient with these three complications in thebackground of a hepatitis A virus and hepatitis E virus co-infection.
Highlights
Both hepatitis A virus (HAV) and hepatitis E virus (HEV) are leading causes of acute viral hepatitis in developing countries due to poor sanitary conditions
Hepatitis A is generally an acute, self-limiting liver infection transmitted through the fecal-oral route by a positive-strand RNA virus, the hepatitis A virus (HAV), which causes 10 million infections worldwide each year . [10] Serological and molecular studies have shown that hepatitis E virus (HEV) is globally distributed and is the leading cause of enterically transmitted viral hepatitis illness worldwide
It is estimated that two billion people worldwide are infected with HEV every year, with 14 million symptomatic cases and 300,000 deaths . [11] Considering the similar epidemiological profile of both viruses, it is unsurprising that a dual infection is not uncommon
Summary
Hepatitis A and hepatitis E virus co-infection with right pleural effusion, ascites and acute acalculous cholecystitis. Coinfección por el virus de la hepatitis A y la hepatitis E con derrame pleural derecho, ascitis y colecistitis acalculosa aguda.
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