Abstract
Liver fibrosis is a common outcome of chronic liver injuries including Schistosoma infection.Activation of resident hepatic stellate cells (HSC) into proliferative,contractile,and fibrogenic myofibrosblast is considered the key process driving liver fibrosis.Recent studies have highlighted that HSC plays an important role in both murine and human schistosomiasis liver fibrosis.Studies of the HSC and its interaction with Schistosoma eggs may be pivotal in our understanding of the pathology associated with schistosomiasis liver fibrosis and provide new approaches to prevent and treat schistosomiasis liver fibrosis. Key words: Hepatic stellate cells; Liver fibrosis; Schistosomiasis
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