Abstract
Thy–1, a phenotypic marker of hematopoietic progenitor cells, is also expressed in activated oval cells of the adult rat liver. Thy1+ cells have also been observed in the rat fetal liver and these cells exhibit properties of bipotent hepatic epithelial progenitor cells in vitro. However, the stem-like properties of Thy–1+ fetal liver cells have not yet been fully established and there is no information available concerning the liver repopulation capacity of Thy1+ fetal liver cells. We therefore isolated Thy–1+ cells from ED14 fetal liver and examined their hepatic gene expression profile and characteristics in vitro and proliferative and differentiation potential after transplantation into the adult rat liver in comparison to Thy–1- fetal liver cells.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
