Abstract
The case report from Abdulla and Davidson (Sept 7, p 650) 1 Abdulla KA McD Davidson N A woman who collapsed after painting her soles. Lancet. 1996; 348: 658 Summary Full Text Full Text PDF PubMed Scopus (39) Google Scholar of a woman who collapsed after painting her soles, raises interesting toxicological points for study. If the woman's collapse was related to the topical application of henna, the signs and symptoms of haemolysis and methaemoglobulinaemia would have helped in reaching the diagnosis. 2 Zinkham WH Oski FA Henna: a potential cause of oxidative hemolysis and neonatal hyperbilirubinemia. Pediatrics. 1996; 97: 707-709 PubMed Google Scholar Her serum or plasma glucose-6-phosphate dehydrogenase (G6PD) concentration, which could easily be determined, could have been another useful test for the association of henna with her collapse. I believe that the toxicity of both henna and paraphenylanediamine (“para”), and the possible in vivo toxicological synergism between these compounds 3 Sirhashim M Hamza YO Yahia B et al. Poisoning from henna dye and para-phenylenediamine mixtures in children in Khartoum. Ann Trop Paediatr. 1992; 12: 3-6 PubMed Google Scholar , requires investigation.
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