Abstract

A study of the state of hemostasis and inflammatory markers in patients with post-COVID syndrome was conducted. An increase in the activity of procoagulant factors against the background of high values of inflammatory markers was found. The presence of a history of non-infectious chronic diseases significantly aggravates disorders in the hemostasis system, and the centers of correlation pleiades are the severity of leukocytosis and the degree of decrease in activated partial thromboplastin time. The use of standard therapy and interval hypoxic training for the treatment of post-COVID disorders did not have a significant effect on hemostatic parameters, but the anti-inflammatory effect was clearly manifested. Mesodiencephalic modulation (MDM therapy) had a significant normalizing effect on the coagulogram and inflammatory markers, and its combination with hypoxic exposure slightly enhanced the therapeutic effects. It is suggested that complex physiotherapy is viable in the treatment of post-COVID syndrome by influencing not only hemostasis and inflammatory reactions, but also non-regulatory mechanisms of the brain and respiratory organs.

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