Abstract
Hemorrhagic transformation (HT) is one of the most common life-threatening complications of ischemic stroke. It occurs when peripheral blood extravasates through the damaged blood-brain barrier (BBB) into the brain parenchyma after ischemic stroke. Hyperthyroidism, the most common endocrine disorder, occurs in 0.5−2% of the general population. Hyperthyroidism is known to trigger several cardiovascular system effects, one of which is the occurrence of atrial fibrillation (AF). There is a study that says that the incidence of HT in ischemic stroke patients with AF increases by 22.6%. A 48-year-old man with complaints of weakness of the left arm and leg, dysarthria and dysphagia with onset 2 hours before coming to the emergency department. Radiological examination showed bleeding with surrounding infarction and hyperthyroidism with AF was found. Hyperthyroidism is associated with AF which will increase the incidence of extensive ischemic stroke and the risk of experiencing HT due to damage to the BBB. Keywords: Hemorrhagic transformation (HT); ischemic stroke; hyperthyroidism; atrial fibrillation (AF); risk factors
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