Hemorrhagic cholecystitis with rare imaging presentation: a case report and a lesson learned from neglected medication history of NSAIDs

Xin Zhang,Haifeng Huang,Yun Zhang,Qida Hu,Junsen Wang,Chunjun Zhang

doi:10.1186/s12876-020-01312-0

Abstract

BackgroundGallbladder carcinogenesis, frequently occurredin chronic cholecystitis patients, requires radical resection. We herein describe a hemorrhagic cholecystitis case that failed to be differentiated from gallbladder cancer preoperatively owing to the neglected medication history of long term oral nonsteroidal anti-inflammatory drugs (NSIADs) intake.Case presentationA 57-year-old Chinese female was admitted for right upper quadrant pain with the initial diagnosis of cholecystitis. Radiological studies were unable to exclude the differential diagnosis of suspected gallbladder cancer. During the scheduled radical resection of the suspected lesions, the gross dissection showed an interesting presentation of hemorrhagic cholecystitis, without any pathological evidence of malignancies. Additional postoperative investigation revealed a neglected medication history of long-term NSAIDs use.ConclusionsThis case suggests the importance of preoperative review of medication history and patient education on prescription drug abuse.

Highlights

Gallbladder carcinogenesis, frequently occurredin chronic cholecystitis patients, requires radical resection
This case suggests the importance of preoperative review of medication history and patient education on prescription drug abuse
We reported a hemorrhagic cholecystitis case where we were unable to eliminate the differential diagnosis of gallbladder cancer preoperatively owing to the neglected medication history of long term oral nonsteroidal anti-inflammatory drugs (NSIADs), indicating the

Summary

Introduction

Gallbladder carcinogenesis, frequently occurredin chronic cholecystitis patients, requires radical resection. Conclusions: This case suggests the importance of preoperative review of medication history and patient education on prescription drug abuse. Long term gallstone-associated cholecystitis may increase the risk of gallbladder carcinoma [2, 3], a highly malignant tumor with poor prognosis [4].

Results

Conclusion