Abstract
Venoms of six common Thailand snakes, Agkistrodon rhodostoma (Malayan pit viper), Trimeresurus popiorum (Green pit viper), Vipera russellii siamensis (Thailand Russell's viper), Ophiophagus hannah (King cobra), Bungarus fasciatus (Banded krait), and Naja naja siamensis (Thailand cobra) were investigated for hemorrhagic and proteolytic enzyme activities. Hemorrhage was induced experimentally under rabbit skin by injecting venom subcutaneously. Proteolytic activities of venoms were determined using the substrates casein, p-toluene sulfonyl- l-arginine methyl ester (TAME), N-benzoyl- l-arginine ethyl ester (BAEE), and N-benzoyl-L-tyrosine ethyl ester (BTEE). The possible relationship between hemorrhagic activity and proteolytic activities was discussed.
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