Abstract

SINCE Brougham et al6in 1950 reviewed the literature and reported five new cases of pituitary apoplexy, there has been an increasing interest in the subject. Subsequent physicians22,26,45reporting their clinical experiences have cited other recorded cases so that the total number now stands at or near 85.2-11,13-15,17-26, 30-33,35-49We have recently treated two additional patients with spontaneous hemorrhage into pituitary adenomata. The details of these are reported here. Clinical Summaries Case1.—A 63-year-old bricklayer was transferred from another hospital on April 29, 1960, for evaluation of headache, diplopia, drowsiness, nausea, and vomiting of five days duration. In 1954 a routine chest x-ray had shown multiple pulmonary densities which were thought to represent silicosis. However, metastatic tumor was considered, and a lateral skull film taken as part of a routine metastatic bone series showed an enlarged sella turcica. Endocrine studies showed normal 17-ketosteroid and 17-hydroxysteroid excretion values

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