Abstract
A hemolytic transfusion reaction in an A2B patient due to anti‐A1 is described. Anti‐A1 was first detected simultaneously with the removal of transfused A1 red blood cells. The antibody in the serum was shown to be of both the IgM and IgG class, but only IgG was demonstrated on and eluted from sensitized, transfused red blood cells. 51Cr survival studies of A1 red blood cells demonstrated the hemolytic capability of this antibody on two occasions.
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