Abstract
IF one defines hemolytic anemias as those in which the life-span of the red cell is diminished, most anemias are hemolytic. Practically, however, it is useful to confine the term to anemias in which shortening of the red-cell life-span is the principal cause of the anemia. The rate of red-cell destruction in such anemias ordinarily exceeds twice the normal and may be ten or twelve times the normal rate. When this rate exceeds the compensatory efforts of the bone marrow anemia ensues. Accordingly, therapy is directed toward restoring the equilibrium between the rates of destruction and production, either by slowing . . .
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