Abstract
Young female diagnosed case of SLE with secondary APLA presented with severe symptomatic anemia, CBC revealed Macrocytic anemia (MCV 129), PBF was suggestive of megaloblastic anemia. Patient was put on treatment parenteral vitamin B12 and folic acid. Anemia worsened; patient was reevaluated and found to have autoimmune hemolytic anemia. Responded to steroids optimally. Macrocytosis in SLE is secondary to folate deficiency and ovalocytosis. JMS 2015; 18(2):156-157
Highlights
Young female diagnosed case of SLE with secondary APLA presented with severe symptomatic anemia, CBC revealed Macrocytic anemia (MCV 129), PBF was suggestive of megaloblastic anemia
Anaemia responded to steroids optimally on megaloblastic treatment anaemia worsened from 4gms/dl to 3.4 gms/dl.Hb
Autoimmune haemolytic anaemia has been reported in 10% of patients with SLE1.The AIH anaemia can be coomb’s positive or coomb’s negative
Summary
Young female diagnosed case of SLE with secondary APLA presented with severe symptomatic anemia, CBC revealed Macrocytic anemia (MCV 129), PBF was suggestive of megaloblastic anemia. Past history of DVT Secondary to APLA underlying SLE with RTA on treatment.Family H/O SLE (sister). In revealed CBC:HB 4 gms/dl; TLC 7.37 DLC P47 L38 plat 51000, MCV 129 MCH 44.9 RDWCV 27 RW-SD 91. Corrected reticount 4.43 PBF DLC P67L28M03 NRBC 7/100 WBC.
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
