Abstract

Background: Anemia being the expression of the underlying disease is a global public health problemaffecting both developing as well as developed countries. The RBC indices and platelet count variationamong anemic patients are important to know their association for clinical implications.Materials and Methods: A hospital-based cross-sectional study among anemic patients with hemoglobin<10 gm%, attending Birat Medical College Teaching Hospital, Nepal from 15 May to 15 July 2020 wereanalyzed for RBC indices and platelet count variation. Demographic data, RBC indices, platelet countvariation, and types of anemia were evaluated. Pearson’s correlation coefficient was used for correlatingthe platelet count with RBC indices. A Chi-square test was used to know about the association betweenthe types of anemia and platelet count variation.Results: Out of 150 anemic patients, the female to male ratio was 1.5:1, with the most common agegroup between 40-49 years. There exist high differences between minimum and maximum individualRBC indices (Hb, MCV, MCH, MCH) and platelet count values. The platelet count variation with RBCvalues and MCV had a statistically significant positive and negative correlation respectively. However,the correlation between platelet count variation with hemoglobin concentration level and type of anemiawas positive but statistically not significant.Conclusion: Findings suggest that platelet count variation with RBC indices and types of anemiacorrelated well among anemic patients. Such association will enable the clinicians for diagnosing andtreatment purposes.

Highlights

  • Anemia can be defined as a condition in which the number of red blood cells (RBC) or the hemoglobin (Hb) concentration within them is lower than normal and their oxygen-carrying capacity is insufficient to meet the body’s physiologic needs

  • The objective of this study is to evaluate the correlation of different RBC values and platelet count variation in anemic patients with Hb

  • The correlation between RBC indices and types of anemia with platelet count among anemic patients re-enforces the importance of their association

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Summary

Introduction

Anemia can be defined as a condition in which the number of red blood cells (RBC) or the hemoglobin (Hb) concentration within them is lower than normal and their oxygen-carrying capacity is insufficient to meet the body’s physiologic needs. The World Health Organization defines anemia in adult men as hemoglobin concentration 15 years)

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