Abstract
We report the finding of two abnormal hemoglobins in three Peruvian families: hemaglobin O Arab and Hemoglobin Hofu. In the first case the patient was found to be double heterozygous for hemoglobin O Arab/β thalassaemia and presents a moderate chronic hemolytic anemia. In the second family the propositus had a severe chronic of hemoglobin A/O Arab were asymptomatic. In the third case we report a family with a very mild chronic hemolytic anemia due to the presence of hemoglobyn Hofu. These two abnormal hemoglobin O Arabia was introduced in Peru and described the methodology used in the Laboratory to characterize the abnormal hemoglobins.
Highlights
We report the finding of two abnormal hemoglobins in three Peruvian families: hemaglobin O Arab and Hemoglobin Hofu
In the third case we report a family with a very mild chronic hemolytic anemia due to the presence of hemoglobyn Hofu
Arends T, Garlin G, Guevara JM, Amesty C, Pérez – Bandez O, Lorkin PA, Lehman H, Castillo O
Summary
We report the finding of two abnormal hemoglobins in three Peruvian families: hemaglobin O Arab and Hemoglobin Hofu. These two abnormal hemoglobin O Arabia was introduced in Peru and described the methodology used in the Laboratory to characterize the abnormal hemoglobins. El presente reporte describe dos variedades de hemoglobina encontradas por primera vez en el Perú; una es la hemoglobina O Arabia, descrita originalmente por Ramot y Cols, en Israel al encontrarla en un niño árabe y su hermana [4], y la hemoglobina Hofu, una hemoglobina de muy rara ocurrencia de la cual probablemente no existan muchos casos en el mundo, reportada por primera vez en Japón en 1968 [5] y encontrada en nuestro país en una paciente con cuadro de leve anemia crónica asintomática.
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