Abstract
Background: AVP (arginine vasopressin) shows unique hemodynamic characterisics, as a vasopressor. AVP has been tried in many cathecholamine refractory vasodilatory situations, andsometimes resulted in effective hemodynamic improvement. In dis study, we hypothesized that low dose AVP infusion could recoverthe decreased SVR (systemic vascular resistance) induced by milrinone infusion with minimal effect on PVR (pulmonary vasculr resistance). Methods: Sixteen patients undergoing OPCAB participated in this study. After a loading dose milrinone was infused, low dose vasopressin infusion was started and titrated until the ssremic blood pressure increased by 20%. During the study, hemodynamic factors including pulmonary capillary wedge pressur and cardiac output were measured using a continuous thermodilution technique with a Swan-Ganz catheter. Results: Milrinone infusion reduced both SVR and PVR. And vasopressin infusion increased SVR, but show relatively less effect on PVR. Conclusions: Low-dose vasopressin infusion could be used to recover the SVR decrease caused by milirinone infusion with little effect on PVR.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
