Abstract
Measurement of pulmonary artery pressure(PAP) in preterm infants would be valuable in monitoring their clinical course. The presence of a patent ductus arteriosus (PDA) in this setting provides access to the pulmonary vascular bed by non-invasive means. This study addresses the reliability of Doppler derived (DD) mean, systolic and diastolic pressure measurements in 2 groups of children (Group 1: n=15, age 3.5±4.0yrs, mean PAP 33±16; Group 2 n=5, age 0.6±0.1yrs, mean PAP 77±15) undergoing simultaneous cardiac catheterization. The influence of ductal size on pressure measurement was also assessed.Ductal size (1-9 mm) did not affect results. Pure left to right shunting was noted in group 1, while bidirectional shunting occurred in group 2. Three patients with near systemic PAP showed no significant DD change with 100% oxygen or vasodilator infusion, consistent with measured PAP. PAP can be predicted under varying hemodynamic states by Doppler measurement of PDA shunt velocities.
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