Abstract
Hemodynamic disturbances in patients with infective endocarditis (IE) are complex and might be consequences of various pathogenic processes. Congestive heart failure (CHF) is a major contributor of hemodynamic derangements, but since IE is often a septic disease, reversible myocardial dysfunction as well as septic shock might sometimes dominate or represent additional contributing factors of disturbed hemodynamics. The major cause of CHF is malfunction of affected valves. It occurs with an incidence of 32 % and is often severe. This is why CHF is the most important risk factor associated with poor patient outcome. Results of the project 'International Collaboration on Endocarditis’ related to the characteristics of CHF in patients with IE are presented.
Highlights
Infective endocarditis (IE) is still a serious disease with a high mortality (16 – 20%) overall
The major cause of Congestive heart failure (CHF) is malfunction of affected valves. It occurs with an incidence of 32 % and is often severe. This is why CHF is the most important risk factor associated with poor patient outcome
It is a localized infection involving the heart valves in the majority of patients, but it is often a generalized infection associated with the systemic inflammatory response syndrome and numerous septic metastases in various parts of the body
Summary
Characteristics of local lesions Localisation, complications Characteristics of vegetation (size, consistency, number, Predisposition • Epidemiology • Chronic diseases of valves and other diseases • Foreign materials cy towards a greater incidence in the group of patients older than 74 years, the difference was not statistically significant (figure 3). This is in accordance with other ICE reports. One might expect that because of a worse prognosis for patients with PVIE, E the incidence of CHF is higher compared to native valve disease. We were not able to confirm this. The incidence
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