Abstract

Objective: to evaluate the impact of the algorithm based on a combination of transpulmonary dilution and continuous venous blood oxygen saturation monitoring on perioperative infusion therapy and hemodynamic correction and on the length of postoperative stay in an intensive care unit and at hospital after aortocoronary bypass surgery without extracorporeal circulation. Subjects and methods. The patients were randomized to two hemodynamic monitoring groups: 1) routine monitoring (RM) (n=20) and 2) complex monitoring (CM) (n=20). In the RM group, therapy was based on the values of central venous pressure, mean blood pressure (BPmean), and heart rate (HR). In the CM group, it was founded on the values of intrathoracic blood volume index, BPmean, HR, central venous saturation (ScvO2), and cardiac index (CI). Measurements were made before, during, and 2, 4, and 6 hours after surgery. Results. In the CM group, colloidal solutions and dobutamine were significantly more frequently used, which was followed by increases in ScvO2 and CI as compared with the baseline values. The frequency of use of ephedrine was significantly higher in the RM group. The algorithm based on complex monitoring reduced the time of achieving the criteria for transferring from the intensive care unit and the length of postoperative hospital stay by 15 and 25%, respectively. Conclusion. Thus, the goal-oriented algorithm based on the complex monitoring of hemodynamics and oxygen transport makes it possible to reveal hemodynamic disturbances and correct them early, which can improve an early postoperative period during aortocoronary bypass surgery on the working heart. Key words: aortocoronary bypass surgery, goal-oriented therapy, central venous saturation.

Highlights

  • ĐĄĐ”ĐČĐ”Ń€ĐœŃ‹Đč ĐłĐŸŃŃƒĐŽĐ°Ń€ŃŃ‚ĐČĐ”ĐœĐœŃ‹Đč ĐŒĐ”ĐŽĐžŃ†ĐžĐœŃĐșĐžĐč ŃƒĐœĐžĐČДрсОтДт, ĐșафДЎра Đ°ĐœĐ”ŃŃ‚Đ”Đ·ĐžĐŸĐ»ĐŸĐłĐžĐž Đž Ń€Đ”Đ°ĐœĐžĐŒĐ°Ń‚ĐŸĐ»ĐŸĐłĐžĐž, ĐžŃ‚ĐŽĐ”Đ»Đ”ĐœĐžĐ” Đ°ĐœĐ”ŃŃ‚Đ”Đ·ĐžĐŸĐ»ĐŸĐłĐžĐž, Ń€Đ”Đ°ĐœĐžĐŒĐ°Ń‚ĐŸĐ»ĐŸĐłĐžĐž Đž ĐžĐœŃ‚Đ”ĐœŃĐžĐČĐœĐŸĐč тДрапОО, МУЗ ĐŸĐ”Ń€ĐČая ĐłĐŸŃ€ĐŸĐŽŃĐșая ĐșĐ»ĐžĐœĐžŃ‡Đ”ŃĐșая Đ±ĐŸĐ»ŃŒĐœĐžŃ†Đ° сĐșĐŸŃ€ĐŸĐč ĐŒĐ”ĐŽĐžŃ†ĐžĐœŃĐșĐŸĐč ĐżĐŸĐŒĐŸŃ‰Đž, ĐŃ€Ń…Đ°ĐœĐłĐ”Đ»ŃŒŃĐș

  • Objective: to evaluate the impact of the algorithm based on a combination of transpulmonary dilution and continuous venous blood oxygen saturation monitoring on perioperative infusion therapy and hemodynamic correction and on the length of postoperative stay in an intensive care unit and at hospital after aortocoronary bypass surgery without extracorporeal circulation

  • The patients were randomized to two hemodynamic monitoring groups: 1) routine monitoring (RM) (n=20) and 2) complex monitoring (CM) (n=20)

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Summary

МИОКАРДА НА Đ ĐĐ‘ĐžĐąĐĐźĐ©Đ•Đœ СЕРДЩЕ

ĐŠĐ”Đ»ŃŒ ĐžŃŃĐ»Đ”ĐŽĐŸĐČĐ°ĐœĐžŃ — ĐŸŃ†Đ”ĐœĐžŃ‚ŃŒ ĐČĐ»ĐžŃĐœĐžĐ” Đ°Đ»ĐłĐŸŃ€ĐžŃ‚ĐŒĐ°, ĐŸŃĐœĐŸĐČĐ°ĐœĐœĐŸĐłĐŸ ĐœĐ° ĐșĐŸĐŒĐ±ĐžĐœĐ°Ń†ĐžĐž Ń‚Ń€Đ°ĐœŃĐżŃƒĐ»ŃŒĐŒĐŸĐœĐ°Đ»ŃŒĐœĐŸĐč Ń‚Đ”Ń€ĐŒĐŸĐŽĐžĐ»ŃŽŃ†ĐžĐž Đž ĐœĐ”ĐżŃ€Đ”Ń€Ń‹ĐČĐœĐŸĐłĐŸ ĐŒĐŸĐœĐžŃ‚ĐŸŃ€ĐžĐœĐłĐ° ĐœĐ°ŃŃ‹Ń‰Đ”ĐœĐžŃ ĐČĐ”ĐœĐŸĐ·ĐœĐŸĐč ĐșŃ€ĐŸĐČĐž ĐșĐžŃĐ»ĐŸŃ€ĐŸĐŽĐŸĐŒ, ĐœĐ° ĐżĐ”Ń€ĐžĐŸĐżĐ”Ń€Đ°Ń†ĐžĐŸĐœĐœŃƒŃŽ ĐžĐœŃ„ŃƒĐ·ĐžĐŸĐœĐœŃƒŃŽ тДрапОю Đž ĐșĐŸŃ€Ń€Đ”Đșцою ĐłĐ”ĐŒĐŸĐŽĐžĐœĐ°ĐŒĐžĐșĐž, Đ° таĐșжД ĐœĐ° ĐżŃ€ĐŸĐŽĐŸĐ»Đ¶ĐžŃ‚Đ”Đ»ŃŒĐœĐŸŃŃ‚ŃŒ ĐżĐŸŃĐ»Đ”ĐŸĐżĐ”Ń€Đ°Ń†ĐžĐŸĐœĐœĐŸĐłĐŸ прДбыĐČĐ°ĐœĐžŃ ĐČ ĐŸŃ‚ĐŽĐ”Đ»Đ”ĐœĐžĐž ĐžĐœŃ‚Đ”ĐœŃĐžĐČĐœĐŸĐč тДрапОО Đž ŃŃ‚Đ°Ń†ĐžĐŸĐœĐ°Ń€Đ” про Đ°ĐŸŃ€Ń‚ĐŸĐșĐŸŃ€ĐŸĐœĐ°Ń€ĐœĐŸĐŒ ŃˆŃƒĐœŃ‚ĐžŃ€ĐŸĐČĐ°ĐœĐžĐž бДз ОсĐșусстĐČĐ”ĐœĐœĐŸĐłĐŸ ĐșŃ€ĐŸĐČĐŸĐŸĐ±Ń€Đ°Ń‰Đ”ĐœĐžŃ. ЕщД ĐŸĐŽĐœĐžĐŒ ĐœĐ°ĐżŃ€Đ°ĐČĐ»Đ”ĐœĐž Đ”ĐŒ ĐŒĐŸĐœĐžŃ‚ĐŸŃ€ĐžĐœĐłĐ° про АКй бДз ИК яĐČĐ»ŃĐ”Ń‚ŃŃ Ń€Đ°ĐœĐœĐ”Đ” ĐČыяĐČ Đ»Đ”ĐœĐžĐ” тĐșĐ°ĐœĐ”ĐČĐŸĐč ĐłĐžĐżĐŸĐșсОО, ĐșĐŸŃ‚ĐŸŃ€Đ°Ń ĐŒĐŸĐ¶Đ”Ń‚ ŃĐŸŃ…Ń€Đ°ĐœŃŃ‚ŃŒŃŃ, ĐœĐ”ŃĐŒĐŸŃ‚Ń€Ń ĐœĐ° ĐœĐŸŃ€ĐŒĐ°Đ»ŃŒĐœŃ‹Đ” Đ·ĐœĐ°Ń‡Đ”ĐœĐžŃ ŃŃ€Đ”ĐŽĐœĐ”ĐłĐŸ Đ°Ń€Ń‚Đ”Ń€ĐžĐ°Đ»ŃŒ ĐœĐŸĐłĐŸ ĐŽĐ°ĐČĐ»Đ”ĐœĐžŃ (СрАД), Ń†Đ”ĐœŃ‚Ń€Đ°Đ»ŃŒĐœĐŸĐłĐŸ ĐČĐ”ĐœĐŸĐ·ĐœĐŸĐłĐŸ ĐŽĐ°ĐČлД ĐœĐžŃ (ЩВД), Ń‡Đ°ŃŃ‚ĐŸŃ‚Ń‹ ŃĐ”Ń€ĐŽĐ”Ń‡ĐœŃ‹Ń… ŃĐŸĐșŃ€Đ°Ń‰Đ”ĐœĐžĐč (ЧХХ) Đž Ń‚Đ”ĐŒĐżĐ° ĐŽĐžŃƒŃ€Đ”Đ·Đ°. В сĐČŃĐ·Đž с ŃŃ‚ĐžĐŒ, Ń†Đ”Đ»ŃŒŃŽ ĐœĐ°ŃˆĐ”ĐłĐŸ ĐžŃŃĐ»Đ”ĐŽĐŸĐČĐ°ĐœĐžŃ яĐČĐž Đ»Đ°ŃŃŒ ĐŸŃ†Đ”ĐœĐșĐ° ĐČĐŸĐ·ĐŽĐ”ĐčстĐČоя Đ°Đ»ĐłĐŸŃ€ĐžŃ‚ĐŒĐ°, ĐŸŃĐœĐŸĐČĐ°ĐœĐœĐŸĐłĐŸ ĐœĐ° ĐșĐŸĐŒĐżĐ»Đ”ĐșŃĐœĐŸĐŒ ĐŒĐŸĐœĐžŃ‚ĐŸŃ€ĐžĐœĐłĐ” ĐłĐ”ĐŒĐŸĐŽĐžĐœĐ°ĐŒĐžĐșĐž Đž Ń‚Ń€Đ°ĐœŃĐżĐŸŃ€Ń‚Đ° ĐșĐžŃĐ»ĐŸŃ€ĐŸĐŽĐ°, ĐœĐ° ĐżĐ”Ń€ĐžĐŸĐżĐ”Ń€Đ°Ń†ĐžĐŸĐœĐœŃƒŃŽ ĐžĐœŃ„ŃƒĐ·ĐžĐŸĐœĐœŃƒŃŽ тДра пою Đž ĐșĐŸŃ€Ń€Đ”Đșцою ĐłĐ”ĐŒĐŸĐŽĐžĐœĐ°ĐŒĐžĐșĐž, Đ° таĐșжД ĐœĐ° ĐżŃ€ĐŸĐŽĐŸĐ»Đ¶Đž Ń‚Đ”Đ»ŃŒĐœĐŸŃŃ‚ŃŒ ĐżĐŸŃĐ»Đ”ĐŸĐżĐ”Ń€Đ°Ń†ĐžĐŸĐœĐœĐŸĐłĐŸ прДбыĐČĐ°ĐœĐžŃ ĐČ ĐŸŃ‚ĐŽĐ”Đ»Đ” ĐœĐžĐž ĐžĐœŃ‚Đ”ĐœŃĐžĐČĐœĐŸĐč тДрапОО (ОИб) Đž ŃŃ‚Đ°Ń†ĐžĐŸĐœĐ°Ń€Đ” у ĐżĐ°Ń†ĐžĐ”ĐœŃ‚ĐŸĐČ Ń АКй бДз ИК

ĐœĐ°Ń‚Đ”Ń€ĐžĐ°Đ»Ń‹ Đž ĐŒĐ”Ń‚ĐŸĐŽŃ‹
Đ Đ”Đ·ŃƒĐ»ŃŒŃ‚Đ°Ń‚Ń‹ Đž ĐŸĐ±ŃŃƒĐ¶ĐŽĐ”ĐœĐžĐ”
Findings
ĐŸĐŸĐșĐ°Đ·Đ°Ń‚Đ”Đ»ŃŒ ĐżĐŸŃĐ»Đ” ĐžĐœĐŽŃƒĐșцоо
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