Hemodiyaliz Hastalarında Fibromiyalji Sendromu Prevalansı ve Yaşam Kalitesine Etkisi

Abstract

Objective: We evaluated the prevalence of fibromyalgia syndrome (FM) in hemodialysis patients and whether this syndrome was associated with gender, age, duration of hemodialysis, or other laboratory parameters. Methods: The study included 248 patients with chronic kidney disease (CKD) undergoing hemodialysis. The patients were stratified into two groups: patients with FM based on the 2010 American College of Rheumatology diagnostic criteria and patients not meeting these criteria without FM. Quality of life (QOL) was assessed using the Short Form-36 (SF-36) and Kidney Disease Quality of Life-36 (KDQOL-36) questionnaires. Sociodemographic data, laboratory parameters and a marker for adequacy of hemodialysis (Kt/V) were recorded. Results: FM was detected in 33/248 (13.3%) of patients included. All patients diagnosed as FM were female. When all sub-parameters of SF-36 and KDQOL-36 were compared, QOL was lower in the FM group compared to patients without FM (p<0.05). When laboratory parameters, dialysis duration, Kt/V, marital status and BMI were compared, no difference was detected between groups (p>0.05). FM frequency was higher in cases of advanced age, presence of systemic disease and/or hepatitis B and C infection in patients undergoing hemodialysis (p<0.05). In addition, FM frequency was inversely proportional to education level (p<0.05). Conclusion: FM, associated with a significant decrease in QOL, is more commonly seen in CKD patients undergoing dialysis compared to the general population. Thus, it will be helpful to keep FM in mind and to improve QOL in these patients by early diagnosis and treatment.