Abstract

Reconditioning of initially rejected donor lungs during ex vivo lung perfusion (EVLP) may increase the number of patients treated with a lung transplantation. Multiorgan donors often suffer from circulatory instability and therefore may be treated with massive crystalloid fluid infusions, which can result in pulmonary edema. EVLP of the donor lungs with a hyperoncotic perfusate theoretically can decrease the lung water content by absorbing alveolar and interstitial edema. The oncotic pressure of the perfusate, however, will decrease during per-

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