Abstract

Though hemochromatosis is said to be a disease in which there is a bronzing of the skin and a definite diabetic condition as determined by the analysis of sugar in the urine, it is of interest to note that in the two cases here reported neither patient had the so-called bronzing and only one showed sugar in the urine, that sign appearing for the first time immediately prior to death. The physical signs were closely allied in both cases, allowing, of course, some time for the progress of the disease in the younger brother. The dominant symptoms were pain in the epigastrium, tenderness over the edge of the liver and a history of excessive drinking which usually occurred over a week-end. Mallory's experimental observations, showing copper poisoning and the excessive use of improperly distilled liquors as probable causative factors of hemochromatosis, were demonstrated in these two cases. The fraternal relationship

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