Abstract
The aerial parts of Artemisia amygdalina Decne yielded ludartin (1), a cytotoxic guaianolide in bulk quantities. Ludartin was converted into antitumor arglabin via a simple and efficient three step reaction pathway. The reaction process involves a regioselective ring opening, followed by stereoselective epoxidation and finally the selective dehydration to afford the desired arglabin in excellent yield (51%, overall yield). This methodology makes Artemisia amygdalina Decne an easily accessible alternate source of arglabin (6).
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
