Abstract
Aims: Hemispheric polymicrogyria (HPMG) often causes unilateral spastic cerebral palsy and severe therapy-resistant epilepsy. The most effective treatment regarding seizure freedom is hemispherotomy. Prediction of hand function after hemispherotomy is challenging, as PMG can not only harbor function, but also induce interhemispheric reorganization. Previous studies showed preserved postoperative grasp function when the paretic hand was controlled via ipsilateral corticospinal projections; whether such patients can show a deterioration of hand function is, however, not known.
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