Hemijski sastav alkaloidnog ekstrakta izolovanog iz nadzemnog dela biljke Hylotelephium spectabile (Boreau) H. Ohba x telephium (L.) H. Ohba

Abstract

There are many motives to study alkaloids within Crassulaceae family, such as chemotaxonomic consideration of alkaloid distribution and evaluation of their biological potential. Data on alkaloids from Sedum telephium (syn. H. telephium) aroused interest for further alkaloid investigation within the genus Hylotelephium H. Ohba. Thus, the aim of this study was to investigate and characterize other plant sources of alkaloids from the same genus. An alkaloid extract (AE-HS) was isolated from fresh aerial parts of a cultivated hybrid H. spectabile x telephium. The chemical composition of AE-HS was determined by GC-MS (gas chromatography - mass spectrometry) method. Eight components were identified, which made up 91.8% of the sample. The most present component of AE-HS was g-crotonolactone (78.6%) followed by 3-methyl-2-butenal (8.6%) and (E)-coniferyl alcohol (2.8%). Nicotine was identified as the only alkaloid in the AE-HS (0.4%). Along with many non-alkaloid compounds, a previous study found six alkaloids in AE of S. telephium (~7%), suggesting differences from our results. Additionally, alkaloid distribution is limited within other genera of the family and belonging to the same genus does not mean a uniform qualitative composition. Further analyzes of AEs of Hylotelephium taxa would certainly shed light on the pattern of alkaloid distribution.