Abstract

Space-occupying, malignant hemispheric infarction is one of the most devastating forms of ischemic stroke. Until recently, there was no proven treatment. In 2007, results from randomized, controlled trials provided evidence for the benefit of early hemicraniectomy. This paper provides an overview on the current treatment options for malignant ischemic brain infarction, with a focus on hemicraniectomy. We also discuss major unsolved problems and open questions regarding the disease. Finally, we give a perspective on future clinical studies in this field of stroke.

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