Abstract

Drepanocytic anemia is an uncommon hereditary disease in Chile. The heterozygous state of drepanocytic anemia or "sickle trait" has a frequency of 8% among Afro-Americans. A small number of patients carrying hemoglobin S are homozygous, with clinical manifestations of hemolytic anemia and thrombotic disease. Sickle trait is usually asymptomatic. We report a 59-year-old male who presented an acute abdominal pain and dyspnea while staying at high altitude. Six days later, an angio CAT scan showed the presence of a subcapsular splenic hematoma that was managed conservatively. Sickle cell induction with sodium metabisulphite was positive. Hemoglobin electrophoresis confirmed the sickle trait.

Highlights

  • Drepanocytic anemia is an uncommon hereditary disease in Chile

  • We report a 59-year-old male who presented an acute abdominal pain and dyspnea while staying at high altitude

  • An angio CAT scan showed the presence of a subcapsular splenic hematoma that was managed conservatively

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Summary

Introduction

Drepanocytic anemia is an uncommon hereditary disease in Chile. The heterozygous state of drepanocytic anemia or “sickle trait” has a frequency of 8% among Afro-Americans. Hematoma subcapsular esplénico en paciente con rasgo falciforme - D. Ante el cuadro de síndrome esplénico, pese a ser una causa rara, fue estudiado para un posible rasgo falciforme con una prueba de inducción de drepanocitos con metabisulfito de sodio al 2%, que fue positiva (Figura 2A).

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