Abstract
Hematology of layers chickens vaccinated with fowl cholera vaccine and experimentally inoculated with virulent Pasteurella multocida serotypes in Zaria, Nigeria
Highlights
Fowl cholera (FC) remains a significant obstacle due to losses to commercial poultry production in most part of tropical Asia and Africa
The mean serum Alkaline Phosphatase (ALP) concentration significantly increase P≤0.05 in unvaccinated layers inoculated with P. multocida when compared to layers vaccinated and inoculated with P. multocida
Hematology of layers chickens vaccinated with fowl cholera vaccine and experimentally inoculated with virulent Pasteurella multocida serotypes in Zaria, Nigeria
Summary
Fowl cholera (FC) remains a significant obstacle due to losses to commercial poultry production in most part of tropical Asia and Africa. Fowl cholera usually occurs as a fulminating disease with massive bacteraemia, high morbidity and mortality (OIE, 2008). In Nigeria, FC is a major constraint to poultry production and outbreak could cause high mortalities of up to 80% (Abdu, 1990; Odugbo et al, 2004; Akpavi et al, 2011). It was demonstrated that killed FC vaccine protected chickens against homologous challenge. Vaccines have been widely used to prevent FC ; these vaccines generally afforded homologous but not heterologous protection (Petersen et al, 2001). In Nigeria, Dashe et al (2013) reported P. multocida serotypes A:1, A:3 and A:4 and found that P. multocida serotype A:1 and A:3 are causing disease in layers. The objectives were to evaluate some hematological parameters of layers vaccinated with live and inactivated fowl cholera vaccines and inoculated with two virulent P. multocida serotypes
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