Hematological status of newly‐calved cows with mineral metabolism disturbance

Abstract

In many livestock farms in Russia there is a problem of correct balancing rations by the major mineral elements. Mineral metabolism disturbance are accompanied by various pathologies from all body systems, including the reproduction function. Timely conducting clinical examination, including hematological examination of all groups of animals allows to prevent the development of negative conditions in the body of cows associated with impaired mineral metabolism. During 2018, 74 blood samples obtained from newly‐calved cows were investigated. All the animals had various signs of mineral failure ‐ lordosis of the lumbar spine, osteomalacia of the caudal vertebrae and the last pair of ribs, weakness of the ligaments of the finger joints. With biochemical research of serum determined that the concentration of total protein averaged 90.7 ± 5.9 g/l, albumin −27.3 ± 3.7 g/l, globulin −61.4 ± 3.2 g/l, which indicates hypoproteinemia with dysproteinemia, with the concentration urea increased to 9.5 ± 0.4 mmol/l. The alkaline phosphatase level in fresh cows was 122.1 ± 11.1 IU/l, AST activity was 130.8 ± 5.6 IU/l, and ALT −34.7 ± 3.9 IU/l. The concentration of cholesterol and triglycerides in the blood of the studied animals were quite high and amounted to 8.7 ± 0.3 mmol/l and 0.29 ± 0.06 mmol/l, accordingly, indicating a violation of lipid metabolism. Ca : P ratio in the cows' blood was disturbed and was often 2: 1.9. The amount of total calcium in the blood was at the level of 2.25 ± 0.03 mmol/l, and of phosphorus −2.09 ± 0.03 mmol/l. During the morphological research, it was determined that the number of red blood cells in cows was lower than the reference values and amounted to 4.3 ± 0.4 * 10^6 /μL, the hemoglobin concentration was 84.0 ± 4.8 g /l, anemia was observed in erythropenia and hypochromemia. Also, in cows with signs of impaired mineral metabolism in the postpartum period, a decrease in hematocrit to 29.0 ± 0.5% was observed. The number of white blood cells was within the reference values and was 9.7 ± 0.5 *10^9/l. In the analysis of leukograms, neutrophilia was identified with the appearance of young cell forms, which suggests a possible course of the inflammatory process. Thus, it can be concluded that carrying out timely medical examination of fresh animals in violation of mineral metabolism will allow to assess the prospects for further use of cows and, taking the necessary measures, to extend their productive longevity.This abstract is from the Experimental Biology 2019 Meeting. There is no full text article associated with this abstract published in The FASEB Journal.