HEMATOLOGICAL PROFILE IN CHRONIC KIDNEY DISEASE PATIENTS – A RETROSPECTIVE STUDY

Abstract

Background: Chronic kidney disease (CKD) is linked to a variety of alterations in haematological parameters. The most common abnormality is anaemia, but white cell and platelet counts as well as their functionality may be compromised. Poor overall clinical prognosis is linked to these abnormalities. Aim: To evaluate the hematological changes in CKD patients. Materials and Method: Retrospective study conducted was for a period of 2 months in 60 chronic kidney disease patients who attended the nephrology department of our hospital were recruited for the present study. Data was collected from case record of patients from medical records department. Hematological details such as Hemoglobin (Hb), red Blood Cell (RBC) count, Mean Corpuscular Volume (MCV), Mean corpuscular Hemoglobin(MCH), Mean cell hemoglobin Concentration(MCHC), Red Cell Distribution width (RDW), White blood cell (WBC) count, platelet count and type of anemia were noted. Results were analysed using SPSS 20.0 version. Results: Of the 60 CKD patients, the most common age group was 5th to 6th decade with male predominance (68.3%). Mean age was 56 years. The study revealed that Hemoglobin (Hb), Red Blood Cells (RBC) were low in CKD patients. The most common type of anemia was normocytic normochromic anemia (68.3%). Leucocytosis and thrombocytopenia was seen in 15% and 40% patients respectively. Conclusion: Anaemia was highly prevalent in CKD patients and was signicantly. Hematological parameters can be evaluated for the underlying cause and treated appropriately. The present study might help clinicians understand haematological prole and take necessary steps in the management.