Abstract

314 patients were examined. The dynamics of changes in hematological parameters for assessing the severity of endogenous intoxication and prediction of postoperative pyo-inflammatory complications in surgical treatment of fractures of long bones has been studied. It is established that syndrome of endogenous intoxication by patients with fractures of long bones develops in the first 2 days from the time of injury There is risk of developing infectious complications of postoperative wound by patients whose hematologic indices are not reduced to 3 days before the normal range. The value of the index-day operations above the normal values increases the risk of infectious complications in the wound during subsequent treatment. Infectious inflammation in postoperative wound is characterized by normal LII values and GPI. To assess the risk of complications it is necessary to carry out the KLA at 3nd and 12th days of the postoperative period concerning LII (leukocyte index of intoxication), GPI (hematologic toxicity index), PTI (indicator of the severity of intoxication). Since the various indices of intoxication have predictive value in a certain period of time of injury

Highlights

  • It is established that syndrome of endogenous intoxication by patients with fractures of long bones develops in the first 2 days from the time of injury

  • There is risk of developing infectious complications of postoperative wound by patients whose hematologic indices are not reduced to 3 days before the normal range

  • The value of the index-day operations above the normal values increases the risk of infectious complications in the wound during subsequent treatment

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Summary

ОРИГИНАЛЬНЫЕ СТАТЬИ

Изучена динамика изменения гематологических показателей для оценки тяжести эндогенной интоксикации и прогнозирования послеоперационных гнойно-воспалительных осложнений при оперативном лечении переломов длинных костей. Если значения индексов в день операции превышают границы нормальных величин, увеличивается риск развития инфекционного осложнения в ране при последующем лечении. There is risk of developing infectious complications of postoperative wound by patients whose hematologic indices are not reduced to 3 days before the normal range. To assess the risk of complications it is necessary to carry out the KLA at 3nd and 12th days of the postoperative period concerning LII (leukocyte index of intoxication), GPI (hematologic toxicity index), PTI (indicator of the severity of intoxication). При остеосинтезе переломов костей конечностей инфекционные осложнения в области послеоперационной раны развиваются у 5–10% пациентов [6]. Прогностическое значение различных иммунологических тестов при этих осложнениях показано в работах ряда авторов [2, 4, 9]

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