Hematological, Biochemical and Immunological Responses of Estuarine Catfish Mystus gulio (Hamilton 1822) After Exposure to Lead (Pb)

Abstract

Due to increased industrialization in developing countries some of the toxic substances are being increased in day-to-day life. Living organisms need some trace amounts of metals like copper, manganese, zinc etc. but some of the non-essential toxic heavy metals are also accumulated in the body of living organisms which may cause damages to the immune organs of the organism. The present study investigated the impacts of sublethal dosage of inorganic Lead acetate on the hematological, biochemical and immunological responses of the brackish water fish Mystus gulio. The LC50 at 96 h was determined by the Probit method. The experiment was performed for 30 days of exposure of lead acetate (4 mg/l) to the fish Mystus gulio. After exposure to lead nitrate hematological (hemoglobin, RBC, WBC, PCV, neutrophil, eosinophil and platelet), biochemical (glucose, protein, albumin and globulin) and immunological (IgM) parameters were analyzed. A decrease was seen in the RBC count, hemoglobin, PCV, MCV, MCH, MCHC, protein, albumin and globulin whereas an increase was seen in WBC count, neutrophils, eosinophils, ESR, platelet count, glucose and Immunoglobulin (IgM).