Abstract
Radiation can induce acute radiation sickness in different ways. In this study, we investigatedthe radio-protective efficacy of ginger extract (GE) against the gamma (γ) ray-induced damageon mice. The source of gamma radiation was cobalt 60 (Co-60). GE was administered to miceat a dose of 5 ml/kg intraperitoneally (IP) for 5 consecutive days before exposing them to 8Gray (Gy) (unit of ionizing radiation dose) of Co-60-gamma-radiation. Mice treated with GEbefore irradiation (pretreated group) showed a significant decrease in the mortality of lethally
 irradiated mice. Moreover, spleen weight was significantly increased. Besides, the GE treat-ment facilitated the recovery of white blood cells (WBC), and hemoglobin (HGB) cell number.
 Altogether, the findings indicated that ginger has remarkable effects on mice against hemato-poietic suppression and gastrointestinal damage caused by irradiation.
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