Hemangioma of the thyroid gland in an adolescent with chronic lymphocytic thyroiditis and adenomatous hyperplasia

Abstract

We report a case of benign hemangioma of the thyroid gland which involved one lobe of the thyroid gland in an adolescent female with classic chronic lymphocytic thyroiditis and adenomatous hyperplasia. The lesion produced a clinical picture suspicious for malignancy owing to the presence of a very large cold nodule on scan, lack of response to TSH suppression, and the subsequent development of an enlarged cervical lymph node. The histologic and immunohistologic findings, including positive staining for factor VIII-related antigen,Ulex europaeous lectin, CD31, CD34, and the presence of linear staining for type IV collagen and laminin are consistent with a hemangioma. In our review of the literature, only one other report of a hemangioma of the thyroid gland was found.