Abstract

Heller syndrome in two Iraqi children

Highlights

  • Heller syndrome is a rare heterogeneous clinical syndrome that is distinctive from autism and Asperger syndrome

  • The main aim of this paper is to describe two Iraqi children with Heller syndrome, one of them have changes on brain MRI suggestive of cerebral vasculitis

  • It is characterized by a significant developmental regression resulting in deterioration in behavioral and adaptive functioning including self-help skills with loss of language and social skills after a period of normal development for at least two years

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Summary

Introduction

Heller syndrome is a rare heterogeneous clinical syndrome that is distinctive from autism and Asperger syndrome. It is characterized by a significant developmental regression resulting in deterioration in behavioral and adaptive functioning including self-help skills with loss of language and social skills after a period of normal development for at least two years. The condition was first reported in 1908 by Theodor Heller in his paper “Über Dementia Infantilis”. He called the condition “Dementia infantilis” [1,2,3,4,5]. Pervasive developmental disorders include five chronic disorders marked by early impairment in socialization, communication, and behavior [6,7,8,9]

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