Helium Physicochemical "Recruitment" of Pulmonary Alveols in Prevention of Alveolar Collapse and Prevention of Acute Respiratory Distress in Patients with COVID-19

Abstract

<i>Purpose</i>. Show value warmed up to 95°C. With helium (as part of thermogeliox) in reducing the surface tension water, including liquid and cellular fraction of blood, which normalizes the movement of erythrocytes in the capillaries and preserves the physiological function of the alveolar-capillary space, improving gas exchange in the alveoli. Materials and methods. The data of dynamics of complaints, anamnesis, clinical symptoms, results of laboratory and instrumental studies, results of pathological, pathomorphological and histological manifestations of severe coronavirus pneumonia (CVP) complicated by acute respiratory distress syndrome (ARDS) were analyzed. <i>Results and its discussion</i>. In the complex treatment of severe coronavirus infection (CVI), it is proposed to use the modern innovative medical technology “CIMT”, which includes the modern device “Ingalit B2–01”, inhaling regulated heated to 90–100 C respiratory gas mixture - thermogeliox, consisting of oxygen 20-30% and helium 70-80%, alternating with inhalation of the lungs surfactant with a nebulizer. It is advisable to inject the anticoagulant under the skin. It has been shown that the development of ARDS in CEP is associated with acute coronavirus alveolitis. A quick positive systemic therapeutic effect is the prevention of ARDS in patients with severe CEP when using our proposed "SIMT" is due to a number of physicochemical and physiological effects of thermal helium.