HELICOBACTER PYLORI WORSENING FACTOR OF THE PATIENT'S CONDITION IN PATIENTS WITH LIVER ENCEPHALOPATHY

Abstract

Hepatic encephalopathy is one of the neuropsychiatric reversible syndromes that manifests itself as impairment of brain function. H. pylori plays a vital role in providing a factor in the pathogenesis of peptic ulcer disease, and there is currently debate about its role in hepatic encephalopathy. Statistics from previous studies have shown that in the gastric secretions and at the same time in the blood serum, some association was found associated with high ammonia content. H. pylori is a gramnegative bacterium that mainly live and infect the acid-resistant mucous membrane of the human stomach. environment, and are the main cause of peptic ulcer and gastritis. They are rich in the enzyme urease, which increases the production of ammonia from the lumen of the stomach, passes into the systemic circulation and enters the brain, which is the main cause of hepatic encephalopathy. High blood ammonia levels are also found in patients with hepatic encephalopathy, which may play a role in its pathogenesis