Abstract

Helicobacter pylori is a Gram negative bacterium that cause chronic gastritis, duodenal ulcers and can predispose the gastric cancer. The study aimed to determinate the prevalence of H. pylori infection by different methods of diagnosis in patients submitted to endoscopy. Of the 145 patients included in the study, were collected fragments of gastric mucosa for histological analysis, and for the rapid urease test. The breath test was also performed. The H. pylori infection was detected in 84 (57.9%) patients by histological study, the rapid test of urease was positive in 81 (55,8%) and the breath test in 62 (56,3%). There was no statistically significant difference when comparing the prevalence of infection by different methods of diagnosis. The prevalence of H. pylori infection in our community was lower than that found in the literature for patients with age similar to this study (mean = 53.19 years).

Highlights

  • Helicobacter pylori is considered as the main cause of chronic gastritis throughout the world

  • The aim of this study was to determine the prevalence of H. pylori infection using different methods of diagnosis in patients undergoing upper endoscopy at university hospital of the Universidade Federal do Triângulo Mineiro, in Uberaba, Minas Gerais, Brazil

  • The study was approved by the Ethics Committee of the Universidade Federal do Triângulo Mineiro (UFTM), Uberaba, Minas Gerais (MG), Brazil and was carried out in accordance with the Declaration of Helsinki

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Summary

Introduction

Helicobacter pylori is considered as the main cause of chronic gastritis throughout the world. A small percentage of H. pylori infected individuals will develop severe diseases such as peptic ulcer, gastric carcinoma, or mucosa-associated lymphoid tissue (MALT) lymphoma[1,2]. In Brazil, some studies have demonstrated differences in prevalence of H. pylori infection according to the population evaluated[2,3]. The aim of this study was to determine the prevalence of H. pylori infection using different methods of diagnosis in patients undergoing upper endoscopy at university hospital of the Universidade Federal do Triângulo Mineiro, in Uberaba, Minas Gerais, Brazil

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