Abstract
Helicobacter pylori (H. pylori) has so far infected more than half the global population. It is the most important and controllable risk factor for gastric cancer. The elderly, who are at a higher incidence of the infection, are also commonly found to develop antibiotic resistance. The symptoms, diagnosis, clinical features (of gastric or extra-digestive diseases), and treatment of H. pylori infection in the elderly, are different from that in the non-elderly. Health conditions, including comorbidities and combined medication have limited the use of regular therapies in elderly patients. However, they can still benefit from eradication therapy, thus preventing gastric mucosal lesions and gastric cancer. In addition, new approaches, such as dual therapy and complementary therapy, have the potential to treat older patients with H. pylori infection.
Highlights
Aging is an inexorable process in the human life cycle
H. pylori affects individuals of different age groups, the elderly have a higher prevalence of H. pylori infection, and risk of developing atrophic gastritis, and stomach cancer [6,7,8]
H. pylori infection is associated with the occurrence of peptic ulcers, chronic atrophic gastritis, gastric cancer etc
Summary
Helicobacter pylori (H. pylori) has so far infected more than half the global population. It is the most important and controllable risk factor for gastric cancer. The symptoms, diagnosis, clinical features (of gastric or extra-digestive diseases), and treatment of H. pylori infection in the elderly, are different from that in the non-elderly. Health conditions, including comorbidities and combined medication have limited the use of regular therapies in elderly patients. They can still benefit from eradication therapy, preventing gastric mucosal lesions and gastric cancer. New approaches, such as dual therapy and complementary therapy, have the potential to treat older patients with H. pylori infection
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