Abstract
Objective: To determine the place of two identification tests for Helicobacter pylori infection available in Congo. Materials and Methods: This was a comparative study carried out in two digestive endoscopy centers in Brazzaville from 1 January to 31 May 2018. Symptomatic patients referred for upper gastrointestinal endoscopy were included systematically. The frequency of infection was determined from two identification tests, namely the rapid urease test in gastric biopsies and the detection of antigen (Ag) for the germ in the stool. The criterion for judging the presence of the germ in each patient was the positivity of at least one of the two tests. The McNEMAR X2 test (p Results: During the study period, 137 consenting patients were included, including 62 men and 75 women. The overall incidence of Helicobacter pylori (Hp) infection was 79.6% (109/28). Of the 137 patients, 18 were urease positive only; 6 were looking for Hp Ag in the stool, and 85 were in the two tests. The frequency of infection was 75.2% (103/137) with the rapid urease test and 66.4% (91/137) with the Hp Ag test in stool. The rapid urease test proved more reliable in the diagnosis of Helicobacter pylori infection than the stool antigen test.
Highlights
The rapid urease test proved more reliable in the diagnosis of Helicobacter pylori infection than the stool antigen test
By the rapid urease test “GOLD Hpdry®” from two biopsies about 0.5 mm in diameter taken from the mucosa antral and fundic
In order to optimize the reliability of the results and to evaluate their respective diagnostic performance, we opted for the use of two Helicobacter pylori research tests available in Congo, namely the rapid urease test based on gastric biopsies and the antigen detection test in the stool
Summary
This is a real public health problem in Congo because of the existence of certain factors such as promiscuity, low socio-economic level, lack of hygiene which increases the incidence and prevalence of this infection [4] [5]. In 2013, a similar study conducted in Pakistan seeking to standardize the Hp stool examination method in adults found a better detection sensitivity of Hp infection in stool examination than in gastric biopsies and a better specificity for rapid urease test [10]
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