Abstract
Objective — to assess the degree of Helicobacter pylori infection among the adult patients with chronic gastritis (CG) and its relationship with atrophic changes in the gastric mucosa.Materials and methods. The examinations involved 325 patients suffered from chronic gastritis (214 male and 111 female), from them 188 patients with nonatrophic CG and 137 patients with atrophic CG). The control group consisted of 40 persons (18 female and 22 male) without history of gastrointestinal pathology.Results. The frequency of helicobacteriosis among patients with CG (61.54 %) was significantly higher than in the control group (42.5 %): р = 0.032. The degree of H. pylori infection among patients with non-atrophic (61.17 %) and atrophic (62.04 %) CG did not differ and was significantly higher than in control (p = 0.046 and p = 0.043, respectively). Gender differences in H. pylori infection were not found in the study groups.Conclusions. H. pylori infection is a risk factor for disease in the studied group of adult patients with chronic gastritis: OR = 2.13 (95 % CI: 1.07 — 4.26), р = 0.032. Only the presence of H. pylori infection, without taking into account pathogenicity factors, cannot serve as a prognostic parameter for the development of atrophic changes in the gastric mucosa in patients with chronic gastritis.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Disclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.