Abstract
F28 A cohort of 151 infants and young children aged 1-23 months from a poor peri urban community of Bangladesh were studied for the relationship of Helicobacter pylori colonization with morbidity due diarrhoea. C13 urea breath test was performed to detect the presence of H. pylori infection. Children were followed up at home every alternate day for 6 months and diarrhoea morbidity data were collected. Diarrhoea morbidity was compared between H. pylori positive and H. pylori negative children. Sixty-eight (45%) were H.pylori positive and 83 (55%) were H.pylori negative. During the first one month period following the breath test 3 (4.4%) H.pylori positive and 4 (4.9%) H.pylori negative and diarrhoea. Thirty two 47%) of the children in the positive group and 43 (52%) in the negative group had one or more episodes of diarrhoea during the 6 months follow-up period. Median(range) diarrhoea episodes was 1.0(1.0-4.0) in the H.pylori positive children and 2.0 (1.0-5) in the H.pylori negative children (p=0.19). No significant difference was observed in the cumulative days with diarrhoea. The results of this study suggest that H.pylori colonization is not associated with diarrhoeal morbidity in infants and young children.
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