Abstract
Helicobacter pylori (H.pylori) is involved in the multistep process that finally leads to gastric malignancies. The link of genotypes of H.pylori with clinical diseases remains controversial. The aim of the study was to investigate the H.pylori cytotoxin-associated gene (cagA), cagE and blood group antigen-binding adhesin (babA2) in patients with Intestinal Metaplasia (IM) and Gastritis (G) as a control group. A total of 36 gastric biopsy specimens (antrum & corpus) were obtained from patients with IM and G based on histopathology findings. DNA extraction and PCR were used to detect the presence or absence of bacterial virulence genes (cagA, cagE and babA2).
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