Abstract
Helicobacter pylori (H. pylori) is a highly prevalence microbial infection, that acts as an iron stressor insusceptible individuals the relationship between ferritin and cytokine levels in individuals infected with H.pylori remains controversial. Based on serology testing for anti-H. pylori IgG, participants (70 seropositiveand 70 seronegative aged 30-60 years were enrolled. Serum iron profiles including iron, ferritin, and totaliron-binding capacity, were measured. IL-1? and IL-6 serum levels were compared. The mean value ofinterleukin 1beta (IL-1?) level of patients and controls revealed that H. pylori patients had a significantlyhigher at (P< 0.001) mean of (IL-1?) when compared to the controls, as shown in this study there is positivecorrelation between gastric interleukin 1beta (IL-1?) and iron deficiency anemia (IDA) blood parametersobserved in resent study could be due to the powerful capability of IL-1? in inhibiting gastric acid secretion.The mean value of Interleukin-6 (IL-6)) level of patients and controls revealed that H. pylori patients had asignificantly higher at (P< 0.001) mean of (IL-6) when compared to the controls.
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