Abstract

Sparse-view scanning has great potential for realizing ultra-low-dose computed tomography (CT) examination. However, noise and artifacts in reconstructed images are big obstacles, which must be handled to maintain the diagnosis accuracy. Existing sparse-view CT reconstruction algorithms were usually designed for circular imaging geometry, whereas the helical imaging geometry is commonly adopted in the clinic. In this paper, we show that the sparse-view helical CT (SHCT) images contain not only noise and artifacts but also severe anatomical distortions. These troubles reduce the applicability of existing sparse-view CT reconstruction algorithms. To deal with this problem, we analyzed the three-dimensional (3D) anatomical structure sparsity in SHCT images. Based on the analyses, we proposed a tensor decomposition and anisotropic total variation regularization model (TDATV) for SHCT reconstruction. Specifically, the tensor decomposition works on nonlocal cube groups to exploit the anatomical structure redundancy; the anisotropic total variation works on the whole volume to exploit the structural piecewise-smooth. Finally, an alternating direction method of multipliers is developed to solve the TDATV model. To our knowledge, the paper presents the first work investigating the reconstruction of sparse-view helical CT. The TDATV model was validated through digital phantom, physical phantom, and clinical patient studies. The results reveal that SHCT could serve as a potential solution for reducing HCT radiation dose to ultra-low level by using the proposed TDATV model.

Highlights

  • Excessive radiation in X-ray computed tomography (CT) can cause potential radiation hazard to the patient, raising concerns linked to the increase in cancer risk incidence [1]

  • We introduce a KBR-based tensor decomposition to describe the 4-order low-rank tensors stacked by the corresponding groups of nonlocal cubes and adopt an anisotropic TV (ATV) regularization to characterize the structural piecewise-smooth of sparse-view helical CT (SHCT) images

  • The experiments are conducted in MATLAB 2016b on a Linux OS with a PC workstation configured with an NVIDIA Tesla P40 graphics processing units (GPUs)

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Summary

Introduction

Excessive radiation in X-ray CT can cause potential radiation hazard to the patient, raising concerns linked to the increase in cancer risk incidence [1]. Various low-dose CT (LDCT) imaging techniques have been explored including low-mAs [2], [3], sparse-view [4], [5], limited-view [6], and region-of-interest scanning [7]. Ultra-low-dose levels, e.g., tube currents of 10 to 20 mA and exposure time of 0.5 seconds per rotation, photon starvation and electronic noise can pose big challenges to image reconstruction [9]–[11]. Sparse-view CT (SCT) is one of the most promising alternative strategies for ultra-low-dose scanning by reducing the number of projections and maintaining the mAs of each projection at normal levels [5]. Many methods have been developed to yield high-quality SCT images [13].

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